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I personally have always had to resort to agarose gel separation and extraction when trying to selectively purify at this small size.

Have a look at this link, I would say it sums up pretty much what is achievable using  SPRI :

https://ls.beckmancoulter.co.jp/files/appli_note/Gel_Free_Using_SPRIselect.pdf

(I am in no way affiliated with this company, have never purchased any of their products and can neither advocate for or against them. However, I do like their graphs.)

Cheers

Tim M

• This reply was modified 9 months, 3 weeks ago by admin.

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